A new and potentially prebiotic α-cytidine derivative†
نویسندگان
چکیده
A new α-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-scale synthesis.
منابع مشابه
On the origin of terrestrial homochirality for nucleosides and amino acids.
Before life could start on earth, it was important that the amino acid building blocks be present in a predominant handedness called the L configuration and that the ribose of RNA be predominantly in the D configuration. Because ordinary chemical processes would produce them in equal L and D amounts, it has long been a puzzle how the needed selectivities could have arisen. Carbonaceous chondrit...
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عنوان ژورنال:
دوره 53 شماره
صفحات -
تاریخ انتشار 2017